Events und Presse

Events

Engineering Lymphocytes for the Immunotherapy of Pediatric Cancer

16-09-2022
15:00
Stephen Gottschalk, Department of BMT & Cellular Therapy St. Jude Children’s Research Hospital Memphis, TN
Jan-Henning Klusmann; Evelyn Ullrich, Winfried Wels
Building 32C, Room B15 & virtuell
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The mechanics of NK cell cytotoxicity and opportunities to improve cellular therapies for cancer

09-11-2022
15:30
Jordan Orange, Columbia University & Morgan Stanley Children’s Hospital
Winfried Wels
Lecture Hall Georg-Speyer-Haus
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Pressemeldungen

2022-07-20

Millionen für mehr Freiraum zur Forschung – neues Clinician-Scientist-Programm INDEEP unter der Leitung von Evelyn Ullrich

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2022-03-04

Neue Untergruppe der akuten myeloischen Leukämie entdeckt

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2022-02-03

Neuer Resistenzmechanismus bei der Therapie des Enddarmkarzinoms entdeckt: entzündliche Bindegewebszellen vermindern Ansprechen auf Radiochemotherapie

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Publications

  • Inflammation: the incubator of the tumor microenvironment
    PubMed
  • ACO/ARO/AIO-21 - Capecitabine-based chemoradiotherapy in combination with the IL-1 receptor antagonist anakinra for rectal cancer Patients: A phase I trial of the German rectal cancer study group
    PubMed
  • IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells
    PubMed
  • Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
    PubMed
  • Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis
    PubMed
  • KMT9 Controls Stemness and Growth of Colorectal Cancer
    PubMed
  • The inflammatory pathogenesis of colorectal cancer
    PubMed
  • Immune cell - produced ROS and their impact on tumor growth and metastasis
    PubMed
  • Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis
    PubMed
  • A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer
    PubMed
  • Fructose stimulated de novo lipogenesis is promoted by inflammation
    PubMed
  • AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
    PubMed
  • S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion
    PubMed
  • A framework for advancing our understanding of cancer-associated fibroblasts
    PubMed
  • STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis
    PubMed
  • Inflammation and Cancer: Triggers, Mechanisms, and Consequences
    PubMed
  • Modulating inflammation for cancer therapy
    PubMed
  • Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis
    PubMed
  • Fungi Enter the Stage of Colon Carcinogenesis
    PubMed
  • Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
    PubMed
  • Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells
    PubMed
  • Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis
    PubMed
  • Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
    PubMed
  • NoxO1 Controls Proliferation of Colon Epithelial Cells
    PubMed
  • Canonical NF-κB signaling in myeloid cells promotes lung metastasis in a mouse breast cancer model
    PubMed
  • Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
    PubMed
  • Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
    PubMed
  • Cell plasticity in epithelial homeostasis and tumorigenesis
    PubMed
  • TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis
    PubMed
  • Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer
    PubMed
  • Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
    PubMed
  • EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients
    PubMed
  • Cancer: Tumour stem-cell surprises
    PubMed
  • Mesenchymal Cells in Colon Cancer
    PubMed
  • IKKα controls ATG16L1 degradation to prevent ER stress during inflammation
    PubMed
  • The Irony of Tumor-Induced Inflammation
    PubMed
  • Inflammation and cancer: tissue regeneration gone awry
    PubMed
  • Pseudo-HE images derived from CARS/TPEF/SHG multimodal imaging in combination with Raman-spectroscopy as a pathological screening tool
    PubMed
  • High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis
    PubMed
  • The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine
    PubMed
  • Bcl-2 is a critical mediator of intestinal transformation
    PubMed
  • Lifting the Mist on Gastric Stem Cells
    PubMed
  • Systematic evaluation of the biological variance within the Raman based colorectal tissue diagnostics
    PubMed
  • IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis
    PubMed
  • Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
    PubMed
  • TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases
    PubMed
  • Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells
    PubMed
  • Corrigendum. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
    PubMed
  • Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche
    PubMed
  • Selective in vivo imaging of syngeneic, spontaneous, and xenograft tumors using a novel tumor cell-specific hsp70 peptide-based probe
    PubMed