Events und Presse

Events

5th Rhein-Main Cancer Retreat

07-11-2024 - 08-11-2024
9:00 - 18:00
Various,
DKTK / LOEWE-FCI / MSNZ
Collegium Glashütten
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Beyond conventional CAR-T therapy: Development of theranostic adapter CAR-T for inpatient and outpatient treatment

18-11-2024
14:00 - 15:00
Claudia Arndt, MSNZ/Technische Universität Dresden, Helmholtz-Zentrum Dresden-Rossendorf
MSNZ Frankfurt - Evelyn Ullrich & Tobias Bexte
Georg-Speyer-Haus, Lecture hall, ground floor
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Symposium – TUMOR MICROENVIRONMENT SYSTEMS

03-12-2024 - 04-12-2024
9:00 - 17:00
Various, various
Zuzana Tatarova
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Pressemeldungen

2024-08-23

Neurobiologie: Waschmaschine fürs Gehirn

Zum Artikel

2024-07-09

Faktor in Bindegewebszellen (ZEB1) moduliert Wirksamkeit von Immuntherapie in kolorektalen Karzinomen

Zum Artikel

2024-05-27

Abkömmlinge des Contergan-Wirkstoffs treiben resistente Krebszellen in den Tod

Zum Artikel

Publications

  • A fast protocol for multicenter and multiparametric quantitative MRI studies in brain tumor patients using vendor sequences
    PubMed
  • Gut microbial carcinogen metabolism: another avenue to cancer
    PubMed
  • Pathological tissue changes in brain tumors affect the pH-sensitivity of the T1-corrected apparent exchange dependent relaxation (AREX) of the amide protons
    PubMed
  • Phosphoproteomic Analysis of Signaling Pathways in Lymphomas
    PubMed
  • Updated EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection - Update 1
    PubMed
  • Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway
    PubMed
  • Integrated multi-omics analysis of PBX1 in mouse adult neural stem- and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4
    PubMed
  • Inflammation in a ferroptotic environment
    PubMed
  • EZB-type diffuse large B-cell lymphoma cell lines have superior migration capabilities compared to MCD-type
    PubMed
  • CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells
    PubMed
  • CD16+ as predictive marker for early relapse in aggressive B-NHL/DLBCL patients
    PubMed
  • The Autophagy Receptor SQSTM1/p62 Is a Restriction Factor of HCMV Infection
    PubMed
  • Irradiation alters extracellular vesicle microRNA load in the serum of patients with leukaemia
    PubMed
  • Chem-CRISPR/dCas9FCPF: a platform for chemically induced epigenome editing
    PubMed
  • Data-driven determination of 1H-MRS basis set composition
    PubMed
  • In vivo CAR T cell therapy against angioimmunoblastic T cell lymphoma
    PubMed
  • RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions
    PubMed
  • Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies
    PubMed
  • Persistent Lymph Node Metastases After Neoadjuvant Chemoradiotherapy for Rectal Cancer
    PubMed
  • mFOLFOX6 versus mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214)
    PubMed
  • Integrated analyses reveal two molecularly and clinically distinct subtypes of H3 K27M-mutant diffuse midline gliomas with prognostic significance
    PubMed
  • Imperative role of adaptor proteins in macrophage toll-like receptor signaling pathways
    PubMed
  • Interventional antibiotic treatment replacing antibiotic prophylaxis during allogeneic hematopoietic stem cell transplantation is safe and leads to a reduction of antibiotic administration
    PubMed
  • Editorial: Women in cancer immunity and immunotherapy
    PubMed
  • Cell blebbing novel therapeutic possibilities to counter metastasis
    PubMed
  • Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy
    PubMed
  • Amino acid metabolism in glioma: in vivo MR-spectroscopic detection of alanine as a potential biomarker of poor survival in glioma patients
    PubMed
  • Superoxide dismutase 1 mediates adaptation to the tumor microenvironment of glioma cells via mammalian target of rapamycin complex 1
    PubMed
  • Survival probability of epigenetically defined IDH-wild-type glioblastoma without necrosis or vascular proliferation
    PubMed
  • Chemoradiotherapy plus induction or consolidation chemotherapy as total neoadjuvant therapy for locally advanced rectal cancer: Pooled analysis of the CAO/ARO/AIO-12 and the OPRA randomized phase 2 trials
    PubMed
  • Epigenetic profiling of prostate cancer reveals potential prognostic signatures
    PubMed
  • T cell receptor-directed antibody-drug conjugates for the treatment of T cell-derived cancers
    PubMed
  • Immune profiling and functional analysis of NK and T cells in ataxia telangiectasia
    PubMed
  • Diagnosis of Hirschsprung disease by analyzing acetylcholinesterase staining using artificial intelligence
    PubMed
  • T-cell specific in vivo gene delivery with DART-AAVs targeted to CD8
    PubMed
  • Cranioencephalic functional lymphoid units in glioblastoma
    PubMed
  • Corrigendum: Impact of ATP-citrate lyase catalytic activity and serine 455 phosphorylation on histone acetylation and inflammatory responses in human monocytic THP-1 cells
    PubMed
  • Small duct and large duct type intrahepatic cholangiocarcinoma reveal distinct patterns of immune signatures
    PubMed
  • Identification of a putative molecular subtype of adult-type diffuse astrocytoma with recurrent MAPK pathway alterations
    PubMed
  • Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia
    PubMed
  • Real-world effectiveness of first-line azacitidine or decitabine with or without venetoclax in acute myeloid leukemia patients unfit for intensive therapy
    PubMed
  • Systemic Treatment of Recurrent Hepatocellular Carcinoma after Liver Transplantation: A Multicenter Trial
    PubMed
  • (Auto)immunity in focal epilepsy: mechanisms of (auto‑)immune-inflammatory epileptogenic neurodegeneration
    PubMed
  • ZEB1-mediated fibroblast polarization controls inflammation and sensitivity to immunotherapy in colorectal cancer
    PubMed
  • A Mouse Model of X-Linked Chronic Granulomatous Disease for the Development of CRISPR/Cas9 Gene Therapy
    PubMed
  • Development of a Potent and Selective G2A (GPR132) Agonist
    PubMed
  • Sanglifehrin A mitigates multiorgan fibrosis by targeting the collagen chaperone cyclophilin B
    PubMed
  • Tumour-specific activation of a tumour-blood transport improves the diagnostic accuracy of blood tumour markers in mice
    PubMed
  • Disturbance in cerebral blood microcirculation and hypoxic-ischemic microenvironment are associated with the development of brain metastasis
    PubMed
  • Empowering virus-free CAR immune cell therapies
    PubMed
  • Long-wavelength traveling waves of vasomotion modulate the perfusion of cortex
    PubMed
  • A prognostic neural epigenetic signature in high-grade glioma
    PubMed
  • Engineering of potent CAR NK cells using non-viral Sleeping Beauty transposition from minimalistic DNA vectors
    PubMed
  • Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
    PubMed
  • 2D 1H sLASER Long-TE and 3D 31P Chemical Shift Imaging at 3 T for Monitoring Fasting-Induced Changes in Brain Tumor Tissue
    PubMed
  • Bortezomib promotes the TRAIL-mediated killing of resistant rhabdomyosarcoma by ErbB2/Her2-targeted CAR-NK-92 cells via DR5 upregulation
    PubMed
  • Molecular targets of glucocorticoids that elucidate their therapeutic efficacy in aggressive lymphomas
    PubMed
  • Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial
    PubMed
  • Inflammatory pathways confer resistance to chemoradiotherapy in anal squamous cell carcinoma
    PubMed
  • Nanopore sequencing from formalin-fixed paraffin-embedded specimens for copy-number profiling and methylation-based CNS tumor classification
    PubMed
  • Murine Alox8 versus the human ALOX15B ortholog: differences and similarities
    PubMed
  • Functional genomics identifies N-acetyllactosamine extension of complex N-glycans as a mechanism to evade lysis by natural killer cells
    PubMed
  • Variation in mesenchymal KITL/SCF and IGF1 expression in middle age underlies steady-state hematopoietic stem cell aging
    PubMed
  • Influenza A virus replicates productively in primary human kidney cells and induces factors and mechanisms related to regulated cell death and renal pathology observed in virus-infected patients
    PubMed
  • Checkpoint Inhibitor Monotherapy in Potentially Trial-Eligible or Trial-Ineligible Patients With Metastatic NSCLC in the German Prospective CRISP Registry Real-World Cohort (AIO-TRK-0315)
    PubMed
  • Bone marrow niches for hematopoietic stem cells: life span dynamics and adaptation to acute stress
    PubMed
  • EpiDiP/NanoDiP: a versatile unsupervised machine learning edge computing platform for epigenomic tumour diagnostics
    PubMed
  • Phosphatidylserine externalization as immune checkpoint in cancer
    PubMed
  • Glioma subtype classification from histopathological images using in-domain and out-of-domain transfer learning: An experimental study
    PubMed
  • Early induction of cytokine release syndrome by rapidly generated CAR T cells in preclinical models
    PubMed
  • Clonal hematopoiesis and its impact on the aging osteo-hematopoietic niche
    PubMed
  • Feasibility of Next-generation Sequencing of Liquid Biopsy (Circulating Tumor DNA) Samples and Tumor Tissue from Patients with Metastatic Prostate Cancer in a Real-world Clinical Setting in Germany
    PubMed
  • Future direction of total neoadjuvant therapy for locally advanced rectal cancer
    PubMed
  • Adaptor molecules mediate negative regulation of macrophage inflammatory pathways: a closer look
    PubMed
  • Evolutionary trajectories of small cell lung cancer under therapy
    PubMed
  • Epigenetic control over the cell-intrinsic immune response antagonizes self-renewal in acute myeloid leukemia
    PubMed
  • Fluorescence confocal microscopy-complete digitization of pathology
    PubMed
  • A guideline on the molecular ecosystem regulating ferroptosis
    PubMed
  • Deep-learning-based reconstruction of undersampled MRI to reduce scan times: a multicentre, retrospective, cohort study
    PubMed
  • Development of Selective Pyrido[2,3-d]pyrimidin-7(8H)-one-Based Mammalian STE20-Like (MST3/4) Kinase Inhibitors
    PubMed
  • PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle
    PubMed
  • CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation
    PubMed
  • Digital Pathology
    PubMed
  • Heterogeneity of small duct- and large duct-type intrahepatic cholangiocarcinoma
    PubMed
  • miR-147b mediated suppression of DUSP8 promotes lung cancer progression
    PubMed
  • PC4: A new regulator of cyclin D1 transcript levels
    PubMed
  • Prevalence of TERT Promoter Mutations in Orbital Solitary Fibrous Tumors
    PubMed
  • Tumor associated macrophages transfer ceruloplasmin mRNA to fibrosarcoma cells and protect them from ferroptosis
    PubMed
  • Challenges of automation in quantitative evaluation of liver biopsies : Automatic quantification of liver steatosis
    PubMed
  • The model transferability of AI in digital pathology : Potential and reality
    PubMed
  • Downregulation of V-ATPase V0 Sector Induces Microvillus Atrophy Independently of Apical Trafficking in the Mammalian Intestine
    PubMed
  • Discovery of a Small Molecule Activator of Slack (Kcnt1) Potassium Channels That Significantly Reduces Scratching in Mouse Models of Histamine-Independent and Chronic Itch
    PubMed
  • Smart Conditioning with Venetoclax-Enhanced Sequential FLAMSA + RIC in Patients with High-Risk Myeloid Malignancies
    PubMed
  • Dual Targeting of Glioblastoma Cells with Bispecific Killer Cell Engagers Directed to EGFR and ErbB2 (HER2) Facilitates Effective Elimination by NKG2D-CAR-Engineered NK Cells
    PubMed
  • Intrathecal IgM synthesis as a diagnostic marker in patients with suspected CNS lymphoma
    PubMed
  • Patient-reported outcomes in advanced NSCLC before and during the COVID-19 pandemic: Real-world data from the German prospective CRISP Registry (AIO-TRK-0315)
    PubMed
  • Synthesis and biological evaluation of 1H-pyrrolo[3,2-g]isoquinolines
    PubMed
  • The neuronal transcription factor MEIS2 is a calpain-2 protease target
    PubMed
  • Actinin-4 controls survival signaling in B cells by limiting the lateral mobility of B-cell antigen receptors
    PubMed
  • Histomolecular classification of urothelial carcinoma of the urinary bladder : From histological phenotype to genotype and back
    PubMed