Events und Presse

Events

Symposium – Microbiome

03-12-2025 - 04-12-2025
Various,
Canan Arkan
Georg-Speyer-Haus, Lecture hall, ground floor
Save Event

Pressemeldungen

2025-06-26

Auf dem Hessentag: LOEWE-Projekte machen Medizin von morgen live erlebbar

Zum Artikel

2025-06-10

Neuer Forschungsverbund: Das unheilvolle Netzwerk des Darmtumors

Zum Artikel

2025-04-15

Organoid-Biobank aus Kopf-Hals-Tumoren: Eine neue Ressource zur Erforschung von personalisierten Therapieoptionen

Zum Artikel

Publications

  • Synergistic targeting of cancer cells through simultaneous inhibition of key metabolic enzymes
    PubMed
  • Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase
    PubMed
  • Impact of tumor size and peritumoral edema on outcomes and complications in anterior midline skull base meningiomas
    PubMed
  • No evidence of leukaemia (NEL) as a response criteria in paediatric AML: a multicentre analysis
    PubMed
  • Crystallographic fragment screening reveals ligand hotspots in TRIM21 PRY-SPRY domain
    PubMed
  • CSF1R+ myeloid-monocytic cells drive CAR-T cell resistance in aggressive B cell lymphoma
    PubMed
  • BRAF/MEK inhibition induces cell state transitions boosting immune checkpoint sensitivity in BRAFV600E-mutant glioma
    PubMed
  • Outcome-associated factors in a molecularly defined cohort of central neurocytoma
    PubMed
  • crossNN is an explainable framework for cross-platform DNA methylation-based classification of tumors
    PubMed
  • The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2
    PubMed
  • Chimeric antigen receptor NK-92 cell function is modulated by HLA class I expression of target cells
    PubMed
  • Strategies for CRISPR-based knock-ins in primary human B cells and lymphoma cell lines
    PubMed
  • AI in optimized cancer treatment: laying the groundwork for interdisciplinary progress
    PubMed
  • Quality of Life After Two Sequences of Total Neoadjuvant Treatment in Patients With Locally Advanced Rectal Cancer in the Randomized CAO/ARO/AIO-12 Phase 2 Trial
    PubMed
  • The role of the extracellular matrix protein SPOCK2 for bone physiology and hematopoiesis
    PubMed
  • Large vesicles from ageing neutrophils: novel safeguards for the resolution of inflammation
    PubMed
  • Immune responses after one versus two Influenza A/B vaccinations in patients with multiple myeloma
    PubMed
  • Emerging advances and future opportunities in the molecular and therapeutic landscape of anal cancer
    PubMed
  • Overexpression of KMT9α is associated with poor outcome in cholangiocarcinoma patients
    PubMed
  • Organ preservation after total neoadjuvant therapy for locally advanced rectal cancer (CAO/ARO/AIO-16): an open-label, multicentre, single-arm, phase 2 trial
    PubMed
  • S1PR4-dependent effects of Etrasimod on primary human myeloid immune cell activation
    PubMed
  • Oncogene aberrations drive medulloblastoma progression, not initiation
    PubMed
  • Native Taylor/Non-Taylor Dispersion-Mass Spectrometry (TNT-MS) Allows Rapid Protein Desalting and Multiplexed, Label-Free Ligand Screening
    PubMed
  • Native Flow-Induced Dispersion Analysis - Mass Spectrometry Enables Automated, Multiplexed Ligand Screening from Conventional, Nonvolatile Buffers
    PubMed
  • Identification and characterization of tertiary lymphoid structures in brain metastases
    PubMed
  • Determination of Minimum Surgical Caseloads for Major Oncologic Resections Using a Population-Attributable Fraction Model of Observational Data in Germany
    PubMed
  • ErbB2/HER2-targeted CAR-NK cells eliminate breast cancer cells in an organoid model that recapitulates tumor progression
    PubMed
  • ACO/ARO/AIO-22 - External beam radiotherapy combined with endorectal high-dose-rate brachytherapy in elderly and frail patients with rectal cancer: A prospective multicentre trial of the German Rectal Cancer Study Group
    PubMed
  • Premature skeletal muscle aging in VPS13A deficiency relates to impaired autophagy
    PubMed
  • Molecular signatures define BAP1-altered meningioma as a distinct CNS tumor with deregulation of Polycomb repressive complex target genes
    PubMed
  • Endorectal brachytherapy for organ preservation in patients with rectal cancer: A paradigm shift?
    PubMed
  • Optimized Long-TE 1H sLASER MR Spectroscopic Imaging at 3T for Separate Quantification of Glutamate and Glutamine in Glioma
    PubMed
  • Inflammatory signaling pathways play a role in SYK inhibitor resistant AML
    PubMed
  • Epidemiology and outcomes of Candida spp. bloodstream infections in cancer patients: a comparative retrospective study from a German tertiary cancer center
    PubMed
  • Migration Dynamics of Human NK Cell Preparations in Microchannels and Their Invasion Into Patient-Derived Tissue
    PubMed
  • Neoadjuvant chemoradiation for patients with resectable locally advanced oral cavity squamous cell carcinoma: Results of the prospective INVERT clinical trial
    PubMed
  • Evolutionary divergence in CTCF-mediated chromatin topology drives transcriptional innovation in humans
    PubMed
  • Prospective, multicenter validation of a platform for rapid molecular profiling of central nervous system tumors
    PubMed
  • AMP-activated protein kinase mediates adaptation of glioblastoma cells to conditions of the tumor microenvironment
    PubMed
  • CAR-NK cell therapy combined with checkpoint inhibition induces an NKT cell response in glioblastoma
    PubMed
  • The role of type I interferon signaling in myeloid anti-tumor immunity
    PubMed
  • Frosted DNA: β-Galactosidase Control of Oligonucleotide Activity
    PubMed
  • Chemotherapy before or after preoperative chemoradiotherapy and surgery for locally advanced rectal cancer: 5-year results of the CAO/ARO/AIO-12 trial - a general pairwise comparison
    PubMed
  • Continuous map of early hematopoietic stem cell differentiation across human lifetime
    PubMed
  • Radiation therapy in anal high-grade squamous intraepithelial lesions-a pattern of care analysis in German-speaking countries
    PubMed
  • Single-stage versus two-stage resection for large anterior midline skull base meningiomas with bihemispheric peritumoral edema
    PubMed
  • Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status
    PubMed
  • IL-17RA signaling provides dual tumor-suppressor function during late-stage colorectal carcinogenesis
    PubMed
  • Advantages of 3D printed patient-individual moulds in brachytherapy for facial skin cancer
    PubMed
  • Plasma lipidomic and metabolomic profiles in high-grade glioma patients before and after 72-h presurgery water-only fasting
    PubMed
  • Corrigendum to "mFOLFOX6 versus mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214) and the ABCSG (R-06)": [ESMO Open 9 (2024) 103703]
    PubMed
  • CAR-CIK vs. CAR-T: benchmarking novel cytokine-induced killer cells as solid tumor immunotherapy in ErbB2+ rhabdomyosarcoma
    PubMed
  • LOPAC library screening identifies suramin as a TRIM21 binder with a unique binding mode revealed by crystal structure
    PubMed
  • Empowering Natural Killer Cells to Combat Acute Myeloid Leukemia: Perspective on CAR-NK Cell Therapy
    PubMed
  • Enhanced conversion of T cells into CAR T cells by modulation of the MAPK/ERK pathway
    PubMed
  • Efficacy and safety of immune checkpoint inhibition combined with concurrent chemoradiotherapy in patients with stage III unresectable non-small cell lung cancer: A systematic review and meta-analysis
    PubMed
  • Application-driven validation of posteriors in inverse problems
    PubMed
  • Survival among patients treated with total mesorectal excision or selective watch-and-wait after total neoadjuvant therapy: a pooled analysis of the CAO/ARO/AIO-12 and OPRA randomized phase II trials
    PubMed
  • BRAT1 - a new therapeutic target for glioblastoma
    PubMed
  • Impact of inhibitory KIR ligand mismatch and other variables on outcomes following myeloablative posttransplant cyclophosphamide-based T-cell-replete haploidentical bone marrow transplantation
    PubMed
  • Expression of claudin-18.2 in cholangiocarcinoma: a comprehensive immunohistochemical analysis from a German tertiary centre
    PubMed
  • Towards interactive AI-authoring with prototypical few-shot classifiers in histopathology
    PubMed
  • Author Correction: Octyl itaconate enhances VSVΔ51 oncolytic virotherapy by multitarget inhibition of antiviral and inflammatory pathways
    PubMed
  • DNA methylation-based analysis reveals accelerated epigenetic aging in giant cell-enriched adult-type glioblastoma
    PubMed
  • Impaired SARS-CoV-2-Specific CD8+ T Cells After Infection or Vaccination but Robust Hybrid T Cell Immunity in Patients with Multiple Myeloma
    PubMed
  • European Association of Neuro-Oncology guideline on molecular testing of meningiomas for targeted therapy selection
    PubMed
  • Detection of diagnostic somatic copy number alterations from cerebrospinal fluid cell-free DNA in brain tumor patients
    PubMed
  • An AMP-activated protein kinase-PGC-1α axis mediates metabolic plasticity in glioblastoma
    PubMed
  • Establishment of Patient-Derived Organoids from Colorectal Cancer Resection Samples
    PubMed
  • Tumor Response and Its Impact on Treatment Failure in Rectal Cancer: Does Intensity of Neoadjuvant Treatment Matter?
    PubMed
  • Mapping Natural Sugars Metabolism in Acute Myeloid Leukaemia Using 2D Nuclear Magnetic Resonance Spectroscopy
    PubMed
  • Flow cytometry identifies changes in peripheral and intrathecal lymphocyte patterns in CNS autoimmune disorders and primary CNS malignancies
    PubMed
  • A fast protocol for multicenter and multiparametric quantitative MRI studies in brain tumor patients using vendor sequences
    PubMed
  • Gut microbial carcinogen metabolism: another avenue to cancer
    PubMed
  • Pathological tissue changes in brain tumors affect the pH-sensitivity of the T1-corrected apparent exchange dependent relaxation (AREX) of the amide protons
    PubMed
  • Phosphoproteomic Analysis of Signaling Pathways in Lymphomas
    PubMed
  • Updated EANO guideline on rational molecular testing of gliomas, glioneuronal, and neuronal tumors in adults for targeted therapy selection-Update 1
    PubMed
  • Transglutaminase 2 promotes epithelial-to-mesenchymal transition by regulating the expression of matrix metalloproteinase 7 in colorectal cancer cells via the MEK/ERK signaling pathway
    PubMed
  • Integrated multi-omics analysis of PBX1 in mouse adult neural stem- and progenitor cells identifies a transcriptional module that functionally links PBX1 to TCF3/4
    PubMed
  • Inflammation in a ferroptotic environment
    PubMed
  • EZB-type diffuse large B-cell lymphoma cell lines have superior migration capabilities compared to MCD-type
    PubMed
  • CRISPR/Cas9 editing of NKG2A improves the efficacy of primary CD33-directed chimeric antigen receptor natural killer cells
    PubMed
  • CD16+ as predictive marker for early relapse in aggressive B-NHL/DLBCL patients
    PubMed
  • The Autophagy Receptor SQSTM1/p62 Is a Restriction Factor of HCMV Infection
    PubMed
  • Dual Centrifugation-Based Screening for pH-Responsive Liposomes
    PubMed
  • Irradiation alters extracellular vesicle microRNA load in the serum of patients with leukaemia
    PubMed
  • Chem-CRISPR/dCas9FCPF: a platform for chemically induced epigenome editing
    PubMed
  • A data-driven algorithm to determine 1H-MRS basis set composition
    PubMed
  • In vivo CAR T cell therapy against angioimmunoblastic T cell lymphoma
    PubMed
  • RUNX1 interacts with lncRNA SMANTIS to regulate monocytic cell functions
    PubMed
  • Bispecific killer cell engagers employing species cross-reactive NKG2D binders redirect human and murine lymphocytes to ErbB2/HER2-positive malignancies
    PubMed
  • Persistent Lymph Node Metastases After Neoadjuvant Chemoradiotherapy for Rectal Cancer
    PubMed
  • mFOLFOX6 versus mFOLFOX6 + aflibercept as neoadjuvant treatment in MRI-defined T3-rectal cancer: a randomized phase-II-trial of the German Rectal Cancer Study Group (CAO/ARO/AIO 0214)
    PubMed
  • Integrated analyses reveal two molecularly and clinically distinct subtypes of H3 K27M-mutant diffuse midline gliomas with prognostic significance
    PubMed
  • Imperative role of adaptor proteins in macrophage toll-like receptor signaling pathways
    PubMed
  • Interventional antibiotic treatment replacing antibiotic prophylaxis during allogeneic hematopoietic stem cell transplantation is safe and leads to a reduction of antibiotic administration
    PubMed
  • Editorial: Women in cancer immunity and immunotherapy
    PubMed
  • Cell blebbing novel therapeutic possibilities to counter metastasis
    PubMed
  • Neutralizing IL-38 activates γδ T cell-dependent antitumor immunity and sensitizes for chemotherapy
    PubMed
  • Amino acid metabolism in glioma: in vivo MR-spectroscopic detection of alanine as a potential biomarker of poor survival in glioma patients
    PubMed