Events and Media

Events

Enhancing interpretation of omics data – interactivity meets reproducibility

29-11-2023 - 29-11-2023
11:30 - 12:30
Federico Marini , Genomic Statistics and Bioinformatics Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI)
Canan Arkan
Georg-Speyer-Haus, Lecture hall, ground floor
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Modulating the Tumor Micro- and Macroenvironment to Overcome Therapy Resistance in Gastrointestinal Cancer

04-12-2023 - 04-12-2023
13:00 - 14:00
Joseph Tintelnot, Mildred-Scheel-Nachwuchszentrum (MSNZ) Universitätsklinikum Hamburg-Eppendorf
MSNZ Frankfurt
Georg-Speyer-Haus, Lecture hall, ground floor
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Modelling Cancer-Microbe Interactions with Organoids and Organs-on-a-Chip

12-12-2023 - 12-12-2023
11:00 - 12:00
Jens Puschhof, German Cancer REsearch Center (DKFZ)
Canan Arkan
Georg-Speyer-Haus, Lecture hall, ground floor
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3rd Frankfurt Cancer Conference 2024 „Targeting the tumor-host interface“.

28-08-2024 - 30-08-2024
Various
Campus Westend, Auditorium Complex, Goethe University, Frankfurt am Main, Germany
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Press Releases

2023-11-15

Florian Greten is listed as Highly Cited Researcher 2023

To the article

2023-11-12

Henner Farin is accepted into the Heisenberg Program of the German Research Foundation (DFG)

To the article

2023-08-02

Canan Arkan appointed Professor for Tumor Metabolism at LOEWE-Centre FCI & Georg-Speyer-Haus

To the article

Publications

  • Colorectal Cancer Organoid-Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
    PubMed
  • Pathogenetic mechanisms and therapeutic approaches of acute-to-chronic liver failure
    PubMed
  • Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy
    PubMed
  • Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade
    PubMed
  • Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression
    PubMed
  • Cancer-Associated Fibroblasts in Inflammation and Antitumor Immunity
    PubMed
  • Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation
    PubMed
  • Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
    PubMed
  • Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer
    PubMed
  • Image-guided radiotherapy in an orthotopic mouse model of rectal cancer
    PubMed
  • Inflammation: the incubator of the tumor microenvironment
    PubMed
  • ACO/ARO/AIO-21 - Capecitabine-based chemoradiotherapy in combination with the IL-1 receptor antagonist anakinra for rectal cancer Patients: A phase I trial of the German rectal cancer study group
    PubMed
  • IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells
    PubMed
  • Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
    PubMed
  • Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis
    PubMed
  • KMT9 Controls Stemness and Growth of Colorectal Cancer
    PubMed
  • The inflammatory pathogenesis of colorectal cancer
    PubMed
  • Immune cell - produced ROS and their impact on tumor growth and metastasis
    PubMed
  • Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis
    PubMed
  • A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer
    PubMed
  • Fructose stimulated de novo lipogenesis is promoted by inflammation
    PubMed
  • AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
    PubMed
  • S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion
    PubMed
  • A framework for advancing our understanding of cancer-associated fibroblasts
    PubMed
  • STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis
    PubMed
  • Inflammation and Cancer: Triggers, Mechanisms, and Consequences
    PubMed
  • Modulating inflammation for cancer therapy
    PubMed
  • Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis
    PubMed
  • Fungi Enter the Stage of Colon Carcinogenesis
    PubMed
  • Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
    PubMed
  • Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells
    PubMed
  • Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis
    PubMed
  • Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
    PubMed
  • NoxO1 Controls Proliferation of Colon Epithelial Cells
    PubMed
  • Canonical NF-κB signaling in myeloid cells promotes lung metastasis in a mouse breast cancer model
    PubMed
  • Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
    PubMed
  • Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
    PubMed
  • Cell plasticity in epithelial homeostasis and tumorigenesis
    PubMed
  • TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis
    PubMed
  • Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer
    PubMed
  • Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
    PubMed
  • EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients
    PubMed
  • Cancer: Tumour stem-cell surprises
    PubMed
  • Mesenchymal Cells in Colon Cancer
    PubMed
  • IKKα controls ATG16L1 degradation to prevent ER stress during inflammation
    PubMed
  • The Irony of Tumor-Induced Inflammation
    PubMed
  • Inflammation and cancer: tissue regeneration gone awry
    PubMed
  • Pseudo-HE images derived from CARS/TPEF/SHG multimodal imaging in combination with Raman-spectroscopy as a pathological screening tool
    PubMed
  • High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis
    PubMed
  • The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine
    PubMed