Events and Media

Events

Science FACTion – Lecture & Workshop

06-06-2023
11:00
Nicolas Wöhrl & Peter Kohl, University Duisburg-Essen
FCI / MSNZ
Georg-Speyer-Haus, Lecture hall, ground floor
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The microbiome as cause and potential therapy in cancer

07-06-2023 - 07-06-2023
14:00 - 15:00
Michael Scharl, University Hospital Zurich
Canan Arkan
Georg-Speyer-Haus, Lecture hall, ground floor
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FCI Lecture – Deciphering and re-engineering the immune response to cancer

14-06-2023
12:30
Brad Nelson, Deeley Research Centre BC Cancer – Victoria, Canada
Karl H. Plate
Georg-Speyer-Haus, Lecture hall, ground floor
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Perspective Lecture: Molecular Precision Oncology: Approaches and Perspective

16-06-2023
15:00
Peter Lichter - Rolf-Sammet-Guest Professorship 2023, Nationales Centrum für Tumorerkrankungen (NCT) / DKFZ, Heidelberg
Hubert Serve
Georg-Speyer-Haus, Lecture hall, ground floor
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tba

19-06-2023
15:00tba
Toshiro Sato, Keio University, Japan
Florian Greten
Georg-Speyer-Haus, Lecture hall, ground floor
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11th UCT Science Day

21-06-2023
9:00
Various,
UCT Frankfurt-Marburg
University Hospital Marburg
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Immuno-evasive stem cell programs in breast cancer metastasis

10-07-2023
15:00
Toni Celià-Terrassa, Hospital del Mar Medical Research Institute (IMIM)
Hind Medyouf
Georg-Speyer-Haus, Lecture hall, ground floor
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Press Releases

2023-02-17

Spatial Biology Lab @ Edinger Institute

To the article

2023-02-01

Ferroptosis Enables Immune Therapies to Fight Against Liver tumors and Liver Metastases

To the article

2022-12-09

LOEWE Center “Frankfurt Cancer Institute” funded with 18 million euros for another three years

To the article

Publications

  • Synthetic enforcement of STING signaling in cancer cells appropriates the immune microenvironment for checkpoint inhibitor therapy
    PubMed
  • Combining ferroptosis induction with MDSC blockade renders primary tumours and metastases in liver sensitive to immune checkpoint blockade
    PubMed
  • Loss of SUV420H2-Dependent Chromatin Compaction Drives Right-Sided Colon Cancer Progression
    PubMed
  • Cancer-Associated Fibroblasts in Inflammation and Antitumor Immunity
    PubMed
  • Colon tumour cell death causes mTOR dependence by paracrine P2X4 stimulation
    PubMed
  • Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy
    PubMed
  • Olfactomedin 4 associates with expression of differentiation markers but not with properties of cancer stemness, EMT nor metastatic spread in colorectal cancer
    PubMed
  • Image-guided radiotherapy in an orthotopic mouse model of rectal cancer
    PubMed
  • Inflammation: the incubator of the tumor microenvironment
    PubMed
  • ACO/ARO/AIO-21 - Capecitabine-based chemoradiotherapy in combination with the IL-1 receptor antagonist anakinra for rectal cancer Patients: A phase I trial of the German rectal cancer study group
    PubMed
  • IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells
    PubMed
  • Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
    PubMed
  • Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis
    PubMed
  • KMT9 Controls Stemness and Growth of Colorectal Cancer
    PubMed
  • The inflammatory pathogenesis of colorectal cancer
    PubMed
  • Immune cell - produced ROS and their impact on tumor growth and metastasis
    PubMed
  • Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis
    PubMed
  • A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer
    PubMed
  • Fructose stimulated de novo lipogenesis is promoted by inflammation
    PubMed
  • AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
    PubMed
  • S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion
    PubMed
  • A framework for advancing our understanding of cancer-associated fibroblasts
    PubMed
  • STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis
    PubMed
  • Inflammation and Cancer: Triggers, Mechanisms, and Consequences
    PubMed
  • Modulating inflammation for cancer therapy
    PubMed
  • Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis
    PubMed
  • Fungi Enter the Stage of Colon Carcinogenesis
    PubMed
  • Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
    PubMed
  • Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells
    PubMed
  • Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis
    PubMed
  • Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
    PubMed
  • NoxO1 Controls Proliferation of Colon Epithelial Cells
    PubMed
  • Canonical NF-κB signaling in myeloid cells promotes lung metastasis in a mouse breast cancer model
    PubMed
  • Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
    PubMed
  • Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
    PubMed
  • Cell plasticity in epithelial homeostasis and tumorigenesis
    PubMed
  • TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis
    PubMed
  • Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer
    PubMed
  • Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
    PubMed
  • EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients
    PubMed
  • Cancer: Tumour stem-cell surprises
    PubMed
  • Mesenchymal Cells in Colon Cancer
    PubMed
  • IKKα controls ATG16L1 degradation to prevent ER stress during inflammation
    PubMed
  • The Irony of Tumor-Induced Inflammation
    PubMed
  • Inflammation and cancer: tissue regeneration gone awry
    PubMed
  • Pseudo-HE images derived from CARS/TPEF/SHG multimodal imaging in combination with Raman-spectroscopy as a pathological screening tool
    PubMed
  • High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis
    PubMed
  • The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine
    PubMed
  • Bcl-2 is a critical mediator of intestinal transformation
    PubMed
  • Lifting the Mist on Gastric Stem Cells
    PubMed