2022-07-20
A new Clinician Scientist Programm INDEEP led by Evelyn Ullrich receives millions to provide time for research
To the articleEvents and Media
Press Releases
2022-03-04
New leukemia subgroup identified for the first time solely by altered proteome
To the article2022-02-04
New resistance mechanism in rectal cancer therapy discovered: inflammatory connective tissue cells reduce response to radiochemotherapy
To the articlePublications
- Inflammation: the incubator of the tumor microenvironment
PubMed - ACO/ARO/AIO-21 - Capecitabine-based chemoradiotherapy in combination with the IL-1 receptor antagonist anakinra for rectal cancer Patients: A phase I trial of the German rectal cancer study group
PubMed - IKKα Promotes Intestinal Tumorigenesis by Limiting Recruitment of M1-like Polarized Myeloid Cells
PubMed - Inflammatory fibroblasts mediate resistance to neoadjuvant therapy in rectal cancer
PubMed - Disruption of Prostaglandin E2 Signaling in Cancer-Associated Fibroblasts Limits Mammary Carcinoma Growth but Promotes Metastasis
PubMed - KMT9 Controls Stemness and Growth of Colorectal Cancer
PubMed - The inflammatory pathogenesis of colorectal cancer
PubMed - Immune cell - produced ROS and their impact on tumor growth and metastasis
PubMed - Inducible mouse models of colon cancer for the analysis of sporadic and inflammation-driven tumor progression and lymph node metastasis
PubMed - A Wnt-Induced Phenotypic Switch in Cancer-Associated Fibroblasts Inhibits EMT in Colorectal Cancer
PubMed - Fructose stimulated de novo lipogenesis is promoted by inflammation
PubMed - AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer
PubMed - S1PR4 ablation reduces tumor growth and improves chemotherapy via CD8+ T cell expansion
PubMed - A framework for advancing our understanding of cancer-associated fibroblasts
PubMed - STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis
PubMed - Inflammation and Cancer: Triggers, Mechanisms, and Consequences
PubMed - Modulating inflammation for cancer therapy
PubMed - Loss of Stat6 affects chromatin condensation in intestinal epithelial cells causing diverse outcome in murine models of inflammation-associated and sporadic colon carcinogenesis
PubMed - Fungi Enter the Stage of Colon Carcinogenesis
PubMed - Therapeutic Ablation of Gain-of-Function Mutant p53 in Colorectal Cancer Inhibits Stat3-Mediated Tumor Growth and Invasion
PubMed - Chronic intestinal inflammation in mice expressing viral Flip in epithelial cells
PubMed - Circulating hypoxia marker carbonic anhydrase IX (CA9) in patients with hepatocellular carcinoma and patients with cirrhosis
PubMed - Mitophagy in Intestinal Epithelial Cells Triggers Adaptive Immunity during Tumorigenesis
PubMed - NoxO1 Controls Proliferation of Colon Epithelial Cells
PubMed - Canonical NF-κB signaling in myeloid cells promotes lung metastasis in a mouse breast cancer model
PubMed - Polyol Pathway Links Glucose Metabolism to the Aggressiveness of Cancer Cells
PubMed - Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis
PubMed - Cell plasticity in epithelial homeostasis and tumorigenesis
PubMed - TGFβ pathway limits dedifferentiation following WNT and MAPK pathway activation to suppress intestinal tumourigenesis
PubMed - Card9-dependent IL-1β regulates IL-22 production from group 3 innate lymphoid cells and promotes colitis-associated cancer
PubMed - Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation
PubMed - EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients
PubMed - Cancer: Tumour stem-cell surprises
PubMed - Mesenchymal Cells in Colon Cancer
PubMed - IKKα controls ATG16L1 degradation to prevent ER stress during inflammation
PubMed - The Irony of Tumor-Induced Inflammation
PubMed - Inflammation and cancer: tissue regeneration gone awry
PubMed - Pseudo-HE images derived from CARS/TPEF/SHG multimodal imaging in combination with Raman-spectroscopy as a pathological screening tool
PubMed - High levels of the soluble programmed death-ligand (sPD-L1) identify hepatocellular carcinoma patients with a poor prognosis
PubMed - The Prosurvival IKK-Related Kinase IKKε Integrates LPS and IL17A Signaling Cascades to Promote Wnt-Dependent Tumor Development in the Intestine
PubMed - Bcl-2 is a critical mediator of intestinal transformation
PubMed - Lifting the Mist on Gastric Stem Cells
PubMed - Systematic evaluation of the biological variance within the Raman based colorectal tissue diagnostics
PubMed - IKKβ acts as a tumor suppressor in cancer-associated fibroblasts during intestinal tumorigenesis
PubMed - Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors
PubMed - TAK1 and IKK2, novel mediators of SCF-induced signaling and potential targets for c-Kit-driven diseases
PubMed - Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells
PubMed - Corrigendum. IL-6R/STAT3/miR-34a feedback loop promotes EMT-mediated colorectal cancer invasion and metastasis
PubMed - Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche
PubMed - Selective in vivo imaging of syngeneic, spontaneous, and xenograft tumors using a novel tumor cell-specific hsp70 peptide-based probe
PubMed