We are seeking a highly motivated, curious, and proactive Doctoral Researcher who will become a part of the research team headed by Dr. Mélanie Tichet at the Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy.
Your project is centered on characterizing suppressive myeloid cells in the tumor and investigating their role in response to therapy to identify actionable, mechanism-based strategies for their remodeling to facilitate immune attack and anti-tumor responses. You will work with preclinical in vivo models, isolate immune cells in vitro, and perform coculture assays and flow cytometry, among other techniques. Additionally, applicants will participate in weekly lab meetings and journal clubs within the vibrant scientific environment of the GSH.
Our group focuses on identifying and understanding the microenvironment-mediated mechanisms of therapeutic resistance and tumor recurrence by employing a wide array of molecular biology, biochemistry, and in vivo approaches. Our lab aims to identify and comprehend the immunoregulatory mechanisms within the TME that suppress T cell immunity at the cellular and molecular levels to improve therapeutic strategies employing state-of-the-art preclinical in vivo cancer models (melanoma, pancreatic cancer, and glioma).
Read more about the research of Mélanie Tichet on our website (https://georg-speyer-haus.de/en/staff/tichet-research/).
- BSc. or MSc. degree in life sciences or biotechnology
- A strong interest in cancer immunology, previous expertise in cancer research is a plus
- High level of motivation, curiosity, communication, proactivity, and learning skills
- Willing to promote a highly collaborative environment
- Organizational skills and a cooperative attitude
- Your spoken and written English is excellent. English is the working language in the lab and institute.
- Development of a scientific profile
- Integration into structures at the FCI
- Participation in further training and qualification programs
- Support in methodological developments and full guidance
- Stimulating, highly collaborative, and friendly atmosphere
- An outstanding international cancer research environment – with a special emphasis on tumor microenvironment and tumor immunology
- Flexible working hours as part of the good work-and-family life balance
- A salary in accordance with the agreement for the public service of the state of Hesse (E13, 65%) with all the usual social benefits, which is available for 3 years with the option for extension
Applications should be submitted electronically to email@example.com as a single PDF containing a cover letter, a CV, two letters of recommendation (with contact information), and certificates.
For further information, please contact Dr. Melanie Tichet (firstname.lastname@example.org).
Our international working environment promotes equal opportunities for all staff regardless of gender, age, cultural background, nationality or impairments under criteria of scientific excellence. Applications from women are explicitly welcome. Disabled individuals will be preferred in case of equal qualification.