Manuel Kaulich

FCI Professur Autophagie in der Tumorpathogenese

Research Focus:

Expertise and Technologies for FCI:

Core Publications

Publications

  • Optimized metrics for orthogonal combinatorial CRISPR screens
    PubMed
  • FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels
    PubMed
  • USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
    PubMed
  • Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy
    PubMed
  • A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth
    PubMed
  • The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions
    PubMed
  • Metabolic Rewiring Is Essential for AML Cell Survival to Overcome Autophagy Inhibition by Loss of ATG3
    PubMed
  • ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression
    PubMed
  • Integrative analysis of epigenetics data identifies gene-specific regulatory elements
    PubMed
  • A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition
    PubMed
  • A subcellular map of the human kinome
    PubMed
  • Minimized combinatorial CRISPR screens identify genetic interactions in autophagy
    PubMed
  • Control of endothelial quiescence by FOXO-regulated metabolites
    PubMed
  • Computational prediction of CRISPR-impaired non-coding regulatory regions
    PubMed
  • Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance
    PubMed