Manuel Kaulich
FCI Professur Autophagie in der Tumorpathogenese
Research Focus:
Expertise and Technologies for FCI:
Publications
- Targeted protein degradation via intramolecular bivalent glues
PubMed - Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
PubMed - The ABL-MYC axis controls WIPI1-enhanced autophagy in lifespan extension
PubMed - ReCo: automated NGS read-counting of single and combinatorial CRISPR gRNAs
PubMed - Deciphering the mitophagy receptor network identifies a crucial role for OPTN (optineurin) in acute myeloid leukemia
PubMed - Optimized metrics for orthogonal combinatorial CRISPR screens
PubMed - FBXL4 ubiquitin ligase deficiency promotes mitophagy by elevating NIX levels
PubMed - USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
PubMed - Protein import motor complex reacts to mitochondrial misfolding by reducing protein import and activating mitophagy
PubMed - A YAP/TAZ-TEAD signalling module links endothelial nutrient acquisition to angiogenic growth
PubMed - The caspase-2 substrate p54nrb exhibits a multifaceted role in tumor cell death susceptibility via gene regulatory functions
PubMed - Metabolic Rewiring Is Essential for AML Cell Survival to Overcome Autophagy Inhibition by Loss of ATG3
PubMed - ERK5 modulates IL-6 secretion and contributes to tumor-induced immune suppression
PubMed - Integrative analysis of epigenetics data identifies gene-specific regulatory elements
PubMed - A Cdk4/6-dependent phosphorylation gradient regulates the early to late G1 phase transition
PubMed
